Pac-Man returned to action in 2013's Pac-Man & the Ghostly Adventures, currently airing as part of Sinclair Broadcasting's Kids Click package.
The series initially aired on DisneyXD here in the US, and concurrently in Japan, which got one extra season out of the series, in addition to some holiday themed episodes that didn't air here, although they could, since the series is also streaming on Netflix.
The biggest difference between this series and the game on which it's based is the premise that the ghosts are secretly pals with ol' Pac, including Pinky, a female ghost with a crush on Pac-Man. Instead of being on what seemed to be Earth in the 1982 ABC series, Pac-Man and pals are on their own world, far more surreal and bizarre thanks to CGI tech.
Let's just give you a tease with the first half of the series opener.
Ghostly Adventures was seemingly dropped by DisneyXD in 2015, but no formal announcement of cancellation was ever made. As noted, it's now on Kids Click, which is experiencing some growing pains in its first few days on the air.