From the Internet Archive comes this rarity.
Back in the early 1950's (they say it is 1950, in fact), Lysol disinfectant didn't have a whole line of subsidiary products. It was a stand alone product all by itself before becoming a household name.
Here's an animated spot, the concept of which would later be copied by Johnson Wax's advertising agents for their Raid line of products. The two talking germs? Voiced by Mel Blanc (naturally).